Louise E. Karagiannidis

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc12q5pn

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CCDC 1016985: Experimental Crystal Structure Determination

The Cambridge Structural Database (2014)

Martina Olivari Riccardo Montis Louise E. Karagiannidis Peter N. Horton Lucy K. Mapp

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Crystal (programming language)

10.5517/cc1347zg

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CCDC 817766: Experimental Crystal Structure Determination

The Cambridge Structural Database (2012)

Louise E. Karagiannidis Philip A. Gale Mark E. Light M. Massi Mark I. Ogden

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccwfyks

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CCDC 817762: Experimental Crystal Structure Determination

The Cambridge Structural Database (2012)

Louise E. Karagiannidis Philip A. Gale Mark E. Light M. Massi Mark I. Ogden

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccwfyfn

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Anion binding and transport properties of cyclic 2,6-bis(1,2,3-triazol-1-yl)pyridines

Organic & Biomolecular Chemistry (2014)

Tamara Merckx Cally J. E. Haynes Louise E. Karagiannidis Harriet J. Clarke Katie J. Holder

A series of cyclic 2,6-bis-(1,2,3-triazolyl)-pyridine anion receptors with thiourea functionalities were synthesized by click reaction of 2,6-diazidopyridine with protected propargylamine followed by condensation of a bisthiocyanate derivative with a series of diamines. Their chloride binding affinities as well as their transport properties in POPC bilayers were examined. These receptors were found to function as anion carriers, which can mediate both Cl(-)/NO3(-) antiport and H(+)/Cl(-) symport, and the transport activity of these hosts were dominated by their lipophilicity.

Triazole

10.1039/c4ob02236j

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CCDC 927445: Experimental Crystal Structure Determination

The Cambridge Structural Database (2013)

Nathalie Busschaert Samuel J. Bradberry Marco Wenzel Cally J. E. Haynes Jennifer R. Hiscock

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc1042lt

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CCDC 1016984: Experimental Crystal Structure Determination

The Cambridge Structural Database (2014)

Martina Olivari Riccardo Montis Louise E. Karagiannidis Peter N. Horton Lucy K. Mapp

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc1347yf

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CCDC 927447: Experimental Crystal Structure Determination

The Cambridge Structural Database (2013)

Nathalie Busschaert Samuel J. Bradberry Marco Wenzel Cally J. E. Haynes Jennifer R. Hiscock

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc1042nw

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CCDC 927446: Experimental Crystal Structure Determination

The Cambridge Structural Database (2013)

Nathalie Busschaert Samuel J. Bradberry Marco Wenzel Cally J. E. Haynes Jennifer R. Hiscock

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc1042mv

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Synthetic transporters for sulfate: a new method for the direct detection of lipid bilayer sulfate transport

Chemical Science (2014)

Nathalie Busschaert Louise E. Karagiannidis Marco Wenzel Cally J. E. Haynes Neil J. Wells

The transmembrane transport of anions by small synthetic molecules is a growing field in supramolecular chemistry and has focussed mainly on the transmembrane transport of chloride. On the other hand, the transport of the highly hydrophilic sulfate anion across lipid bilayers is much less developed, even though the inability to transport sulfate across cellular membranes has been linked to a variety of genetic diseases. Tris-thioureas possess high sulfate affinities and have been shown to be excellent chloride and bicarbonate transporters. Herein we report the sulfate transport abilities of a series of tris-ureas and tris-thioureas based on a tris(2-aminoethyl)amine or cyclopeptide scaffold. We have developed a new technique based on 33S NMR that can be used to monitor sulfate transport, using 33S-labelled sulfate and paramagnetic agents such as Mn2+ and Fe3+ to discriminate between intra- and extravesicular sulfate. Reasonable sulfate transport abilities were found for the reported tris-ureas and tris-thioureas, providing a starting point for the development of more powerful synthetic sulfate transporters that can be used in the treatment of certain channelopathies or as a model for biological sulfate transporters.

Bicarbonate

10.1039/c3sc52006d

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Citations (101)

Louise E. Karagiannidis

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H-Index

i-10 index

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H-Index

i-10 index