K. R. S. Sambasiva Rao

Mizoram University

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K. K. Pulicherla

Department of Science and Technology

K. V. Ramana Rao

Central Institute of Agricultural Engineering

Rajesh Patel

Ahmedabad Civil Hospital

Anmol Kumar

Central Institute of Plastics Engineering and Technology

Mrinmoy Ghosh

Jeju National University

K. S. Prasada Rao

Indian Institute of Horticultural Research

Jenabhai B. Chauhan

Sardar Patel University

P.S. Sha Valli Khan

Yogi Vemana University

Krishna M. Singh

UC Davis Health System

I. Kabeer Ahammad Sahib

Sri Venkateswara University

Cooperative Institutions

Acharya Nagarjuna University

Indian Agricultural Research Institute

Indian Council of Agricultural Research

National Research Centre on Plant Biotechnology

Indian Institute of Chemical Technology

Acharya N. G. Ranga Agricultural University

Bharathiar University

Sri Venkateswara University

Indian Institute of Rice Research

Institute of Medical Sciences

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Differential toxicity of malathion, BHC, and carbaryl to the freshwater fish,Tilapia mossambica (peters)

Bulletin of Environmental Contamination and Toxicology (1983)

Shaik Mahaboob Basha K. S. Prasada Rao K. R. S. Sambasiva Rao K. V. Ramana Rao

Carbaryl

Fresh water fish

10.1007/bf01605472

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Citations (8)

Callus induction and plantlet regeneration in Bixa oreliana L., an annatto-yielding tree

In Vitro Cellular & Developmental Biology - Plant (2002)

P.S. Sha Valli Khan Ekambaranellore Prakash K. R. S. Sambasiva Rao

Callus

Plantlet

10.1079/ivp2001284

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Citations (36)

Detection of fragile site on chromosomes of sub-fertile cattle bulls.

Intas Polivet (2004)

G. S. Prasanthi Rajesh Patel K. R. S. Sambasiva Rao Krishna M. Singh

Chromosomal fragile site

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Variations in quantity and quality of neemoil (Azadirachta indica A.juss) extracted by petroleum ether and ethanol in select areas of Guntur, Andhra Pradesh, India.

Current Trends in Biotechnology and Pharmacy (2011)

T. Satyanandam Gorrepati Rosaiah K. Nirmal Babu Yuxin Rao K. R. S. Sambasiva Rao

Neem oil extracted from seeds of neem trees (Azadirachta indica A.juss) growing in three soil types has showed variations, using petroleum ether and ethanol. Effect of temperature and the influence of solvent on the extraction were studied. Results showed that the maximum oil yield was 42.60% with petroleum ether and 39.17% with ethanol at 50oC. It was observed that the increase in temperature, decreased the iodine value, whereas increased acid, and peroxide values, envisaging that the higher extraction temperature, though gives higher oil yield, decreased the quality of oil. It was evident that petroleum ether (bp 60–80°C) can be effectively used as a good solvent for the extraction of oil in solvent extraction process. Further it was observed that some significant variations in Azadirachtin (980 – 2420 mg/kg), seed protein (27.2 -32.8%) and seed weight (16.8 – 18.9 g) were observed in trees growing in different soil types.

Azadirachta

Petroleum ether

Azadirachtin

Neem Oil

Meliaceae

Non-invasive ventilation

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Citations (2)

Photorespiration studies in Cycas circinalis L. and Cycas beddomei Dyer

Photosynthesis Research (1981)

Chandra S. Prabhakar K. R. S. Sambasiva Rao

Photorespiration

Compensation point

Darkness

Gymnosperm

Light intensity

10.1007/bf00056267

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Citations (1)

Osteoporosis: use of nanoparticles for the treatment of osteoporosis.

Biomedical & Pharmacology Journal (2009)

N. V. Sree P. Udayasri V Suresh K. R. S. Sambasiva Rao

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Citations (2)

Formulation development and in vivo evaluation of pramipexoledihydrochloride monohydrate extended release tablets for Parkinsonâs disease

Der pharmacia lettre (2013)

Kothamasu Soma Sekhar Maddi Venkata Nagabhushanam K. R. S. Sambasiva Rao D. V. R. N. Bhikshapathi

The objective of the present study was to develop and characterize extended release tablets of Pramipexole dihydrochloride monohydrate to be taken once daily. The combination of different polymers like hydroxypropyl methyl cellulose (HPMC K 100M) and Eudragit L 100 in varying concentrations were studied to get the desired extended release profile over a period of 24 h. The granules were evaluated for angle of repose, bulk density, compressibility index, and drug content and found to be satisfactory. Hydroxypropylmethylcellulose (HPMC K100M) at 40% level in combination with methacrylic acid copolymer (Eudragit L100) at 3.3% level produced extended release Pramipexole dihydrochloride monohydrate matrix tablets. The drug release of optimized formulation (F4) was 100% which extended up to 24 h in vitro study. The drug release pattern from the optimized matrix formulation (F4) was diffusion controlled, obeying Higuchi equation. The innovator product Mirapex (0.375 mg) drug release profiles are shown to be followed first order release kinetics. In vivo bioavailability studies were conducted in rabbits and the pharmacokinetic parameters of the best formulation (F4) clearly indicated that the drug release was controlled and maintained constant plasma concentration upto 24 hours. The results suggested that combination of hydrophilic and hydrophobic polymers used in the preparation of extended release Pramipexole dihydrochloride monohydrate tablets, is a suitable method and it can perform therapeutically better.

Extended release

Angle of repose

Innovator

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Genotyping of the polymorphism within exon 3 of prolactin gene in various dairy breeds by PCR RFLP (Brief report)

Archives animal breeding/Archiv für Tierzucht (2008)

A. Ratna Kumari Krishna M. Singh K. J. Soni Rajesh Patel Jenabhai B. Chauhan

Abstract. In mammals, especially dairy cattle the prolactin has important functions like the development of mammary gland affecting milk yield and composition. It has been mapped to chromosome 23 in Bovine (HALLERMAN et al., 1988). A silent A→G transition mutation at the codon for amino acid 103 in exon 3 of bovine prolactin (bPRL) gene gives rise to a polymorphic Rsa I site, has become a popular genetic marker used for genetic characterization of cattle populations by means of PCR-RFLP (MITRA et al., 1995; CHRENEK et al., 1998; DYBUS, 2005). The present study reports on the genotype frequencies observed in various Bos taurus and Bos indicus dairy cattle breeds.

Bovine somatotropin

10.5194/aab-51-298-2008

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Citations (15)

Development and validation of an indirect competitive ELISA for quantification of recombinant staphylokinase in rabbit plasma: Application to pharmacokinetic study

Journal of Immunoassay and Immunochemistry (2015)

Anmol Kumar K. K. Pulicherla K. R. S. Sambasiva Rao

The relatively short circulatory half-life (2–3 min) of staphylokinase is a major drawback in the development of SAK- (staphylokinase) based thrombolytic drug. A rapid and sensitive method, based on indirect competitive ELISA, was developed and validated for quantitative determination of SAK in rabbit plasma. The dynamic range of the assay varied between 0.41 ± 0.16 μg/L and 9.03 ± 0.38 μg/L (R2 = 0.98) for SAK in rabbit plasma. There were no dilution linearity issues apparent with this assay. The precision (% CV) ranged from 4.6–9.7% for the intraassay and from 17.1–19.3% for interassay. This validated method was successfully employed for evaluation of various pharmacokinetic parameters of SAK in rabbit.

Staphylokinase

10.1080/15321819.2015.1126600

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Citations (1)

Effect of malathion on protein synthetic potentiality of the tissues of the teleost, Tilapia mossambica (peters), as measured through incorporation of [14c]amino acids

Toxicology Letters (1984)

I. Kabeer Ahammad Sahib K. R. S. Sambasiva Rao K. V. Ramana Rao

Glutamic acid

10.1016/0378-4274(84)90184-x

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Citations (20)