Ramkrishna Basak

Institut de Chimie des Substances Naturelles

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Manas Chakrabarty

Bose Institute

Yoshihiro Harigaya

Tripura University

Nandita Ghosh

University of Calcutta

I. Safir

Institut de Chimie des Substances Naturelles

Sandipan Sarkar

Biocon (India)

Angéline Chanu

Université de Lille

Hiroaki Takayanagi

Kitasato University

Siméon Arseniyadis

Fırat University

A. Chiaroni

Institut de Chimie des Substances Naturelles

Satarupa Banerjee

Vellore Institute of Technology University

Cooperative Institutions

University of Bradford

Centre National de la Recherche Scientifique

University of Leeds

Bose Institute

Institut de Chimie des Substances Naturelles

Institute of Structural and Molecular Biology

University of Calcutta

University of East Anglia

Centro de Investigaciones Biológicas Margarita Salas

Consejo Superior de Investigaciones Científicas

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Corrigendum to “Reaction of 3/2-formylindoles with TOSMIC: formation of indolyloxazoles and stable indolyl primary enamines” [Tetrahedron 61 (2005) 1793]

Tetrahedron (2005)

Manas Chakrabarty Ramkrishna Basak Yoshihiro Harigaya Hiroaki Takayanagi

Tetrahedron

Primary (astronomy)

10.1016/j.tet.2005.02.037

Cite

Citations (1)

Dry reaction of indoles with carbonyl compounds on montmorillonite K10 clay: a mild, expedient synthesis of diindolylalkanes and vibrindole A

Tetrahedron Letters (2002)

Manas Chakrabarty Nandita Ghosh Ramkrishna Basak Yoshihiro Harigaya

Dry media reaction

Carbonyl group

10.1016/s0040-4039(02)00682-2

Cite

Citations (177)

Bisoxazoline (BOX) Ligand-Metal Complexes:An Emerging Chiral Catalyst

Synlett (2003)

Ramkrishna Basak

C2-symmetric chiral bisoxazoline (BOX) ligand-metal complexes have emerged as an effective catalyst for carrying out a wide range of enantioselective reactions. [1] The presence of a C2-symmetric axis in the bisoxazoline ligands minimizes the number of possible transition states in a particular reaction. [2] Of the various chiral bisoxazoline ligands used, ligands (1-7) with a one carbon bridging between the oxazoline rings are most frequently utilized. Several research groups have utilized these bisoxazoline ligands in combination with a wide range of mild Lewis acids as catalysts for carrying out different enantioselective reactions. [4-13] Recently, chiral BOX-metal(II) complexes covalently anchored to silica and mesoporous MCM-41 have been used as a new heterogenous catalyst for enantioselective Friedel-Crafts hydroxylation. [14] An intriguing feature of the BOX-metal(II) complexes is that the metal(II)-derived chiral Lewis acids shows pronounced counter ion [15a-c] as well as solvent dependence in context of yield, enantioselectivity, rate, and success of reaction. The selectivity observed is due to the fact that the bisoxazoline ligands form six membered metal chelates which are conformationally constrained and the chiral centers in these ligands are located in close proximity to donor nitrogen, thereby imposing a strong directing effect on the catalytic sites. [16]

Oxazoline

Chiral ligand

Chiral Lewis acid

10.1055/s-2003-39914

Cite

Citations (1)

ChemInform Abstract: Synthesis of Nor‐sesquiterpene Spirolactones and Their Steroidal Hybrids Revisited. The Neopentyl Dilemma: Misassignment of One Stereocentre May Necessitate a Completely New Approach.

ChemInform (2015)

I. Safir Angéline Chanu Z. Elkhayat Ramkrishna Basak Siméon Arseniyadis

Abstract The correct C1 configuration in natural pathylactone A (I) is clarified.

10.1002/chin.201515263

Cite

Citations (0)

Synthesis and biological evaluation of colchicine C-ring analogues tethered with aliphatic linkers suitable for prodrug derivatisation

Bioorganic & Medicinal Chemistry Letters (2012)

Jérémie Fournier-Dit-Chabert V. Vinader Ana Rita Santos Mariano Redondo‐Horcajo Aurore Dreneau

Colchicine

Linker

HeLa

10.1016/j.bmcl.2012.09.104

Cite

Citations (21)

Reaction of indole and alkylindoles with ceric ammonium nitrate on silica gel

Journal of Chemical Research (2003)

Manas Chakrabarty Sandipan Sarkar Ramkrishna Basak

Treatment of N-methylindole with CAN-on-SiO 2 furnished 2,2-bis( N-methyl-3′-indolyl)- N-methylindoxyl, whereas that of skatole, N-methyl and N-ethyl skatoles produced the respective 2-nitroskatoles along with 6-nitroskatole and N-methyl-5-nitroskatole.

Ceric ammonium nitrate

Skatole

10.3184/030823403322656012

Cite

Citations (6)

Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility

Organic & Biomolecular Chemistry (2013)

Martin Fisher Ramkrishna Basak Arnout P. Kalverda Colin W. G. Fishwick W. Bruce Turnbull

An approach for designing bioactive small molecules has been developed in which de novo structure-based ligand design (SBLD) was focused on regions of chemical space accessible using a diversity-oriented synthetic approach. The approach was exploited in the design and synthesis of a focused library of platensimycin analogues in which the complex bridged ring system was replaced with a series of alternative ring systems. The affinity of the resulting compounds for the C163Q mutant of FabF was determined using a WaterLOGSY competition binding assay. Several compounds had significantly improved affinity for the protein relative to a reference ligand. The integration of synthetic accessibility with ligand design enabled focus to be placed on synthetically-accessible regions of chemical space that were relevant to the target protein under investigation.

Chemical space

Chemical library

10.1039/c3ob41975d

Cite

Citations (10)

Reaction of 3/2‐Formylindoles with TOSMIC: Formation of Indolyloxazoles and Stable Indolyl Primary Enamines.

ChemInform (2005)

Manas Chakrabarty Ramkrishna Basak Yoshihiro Harigaya Hiroaki Takayanagi

10.1002/chin.200525115

Cite

Citations (0)

Concise Synthesis of Coscinamide B, a Bisindolic Enamide from Marine Sponge.