Francis Martinson

North Dakota State University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Irving Hoffman

University of Malawi

102

Mina C. Hosseinipour

University of North Carolina at Chapel Hill

William C. Miller

University of North Carolina at Chapel Hill

David Chilongozi

African Institute for Development Policy

Myron S. Cohen

University of North Carolina at Chapel Hill

Susan A. Fiscus

University of North Carolina at Chapel Hill

Denise J. Jamieson

Emory University

Charles van der Horst

University of the Witwatersrand

Sascha Ellington

Centers for Disease Control and Prevention

Dumbani Kayira

World Health Organization - Malawi

Cooperative Institutions

University of North Carolina at Chapel Hill

300

Johns Hopkins University

223

Centers for Disease Control and Prevention

195

University of Malawi

166

University of Washington

147

National Institutes of Health

120

Harvard University

Fred Hutch Cancer Center

Columbia University

University of California, San Francisco

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

High contraception use and low pregnancy rate among HIV positive women attending a postnatal program in Lilongwe, Malawi

Contraception (2010)

Eugene K. Campbell Innocent Mofolo Elizabeth Jere Zenabu Mhango Esmie Kamanga

10.1016/j.contraception.2010.04.136

Cite

Citations (2)

Collecting the essence of man: semen collection for HIV transmission studies in sub-Saharan Africa

Sexually Transmitted Infections (2005)

Matthew A. Price Myron S. Cohen Irving Hoffman David Chilongozi Francis Martinson

Efforts to understand male to female sexual transmission of HIV must include semen analysis. Estimating sexual infectiousness using blood HIV RNA concentrations as a surrogate marker may be biased.1 Semen is routinely collected in Europe and the United States for HIV research2 and has recently been collected in clinical trials in sub-Saharan Africa3; however, there are no published data about issues associated with semen collection. We conducted a study at the Central Hospital in Lilongwe, Malawi, from January 2000 to June 2001 to better understand the relation between trichomonas and HIV-1 viral load.4 Men attending STI and dermatology clinics consented and were enrolled. All men with Trichomonas vaginalis and a comparison group of …

Sexual transmission

10.1136/sti.2004.012104

Cite

Citations (8)

The Acceptance and Feasibility of Replacement Feeding at 6 Months as an HIV Prevention Method in Lilongwe, Malawi: Results From the BAN Study

AIDS Education and Prevention (2011)

Megan Parker Margaret E. Bentley Charles Chasela Linda S. Adair Ellen Piwoz

International guidelines recommend EBF to age 6 months among HIV-infected mothers choosing to breast-feed and cessation thereafter if replacement feeding is acceptable, feasible, affordable, sustainable, and safe. When mothers wean, they are challenged to provide an adequate replacement diet. This study investigates the use and acceptability of a lipid-based nutrient supplement (LNS) as a breast-milk substitute when provided to infants (6–12mo) of HIV-positive mothers, as part of the Breast-feeding, Antiretroviral, and Nutrition (BAN) Study. A sub-sample of mothers (n = 45) participated in interviews that explored EBF, weaning, and strategies to feed LNS. Mothers reported several weaning strategies, including gradual reduction of breast-feeding, expressing breast-milk into a cup, and separation of mother and child. LNS, a peanut-based micronutrient fortified paste, was highly accepted and incorporated into the traditional diet. Weaning is a feasible HIV prevention method among this population in Malawi when supported by the provision of LNS as a breast-milk substitute.

10.1521/aeap.2011.23.3.281

Cite

Citations (18)

Acceptance of repeat population-based voluntary counseling and testing for HIV in rural Malawi

California Center for Population Research (2008)

Francis Obare Peter Fleming Philip Anglewicz Rebecca Thornton Francis Martinson

Objective: To examine the acceptance of repeat population-based voluntary counseling and testing (VCT) for HIV in rural Malawi. Methods: Behavioral and biomarker data were collected in 2004 and 2006 from approximately 3,000 adult respondents. In 2004, oral swab specimens were collected and analyzed using enzyme-linked immunosorbent assay (ELISA) and confirmatory Western blot tests while finger-prick rapid testing was done in 2006. We use cross-tabulations with chi-square tests and significance tests of proportions to determine the statistical significance of differences in acceptance of VCT by year, individual characteristics and HIV risk. Results: First, over 90% of respondents in each round accepted HIV test, despite variations in testing protocols. Second, the percentage of individuals who obtained their test results significantly increased from 67% in 2004 when the results were provided in randomly selected locations several weeks after the specimens were collected, to 98% in 2006 when they were made available immediately within the home. Third, whereas there were significant variations in the socio-demographic and behavioral profiles of those who were successfully contacted for a second HIV test, this was not the case for those who accepted repeat VCT. This suggests that variations in the success of repeat testing might come from contacting the individuals rather than from accepting the test or knowing the results. Conclusions: Repeat HIV testing at home by trained health care workers from outside the local area, and with either saliva or blood, is almost universally acceptable in rural Malawi, and thus likely to be acceptable in similar contexts.

Turnover

Source

Cite

Citations (2)

Table of Contents

Contraception (2016)

Dawn Chin‐Quee John Stanback Victoria Graham Lori Freedman Debra Stulberg

Table (database)

10.1016/s0010-7824(16)30056-7

Cite

Citations (0)

The HPTN 024 Study: The efficacy of antibiotics to prevent chorioamnionitis and preterm birth

American Journal of Obstetrics and Gynecology (2006)

Robert L. Goldenberg Anthony Mwatha Jennifer S. Read Samuel Adeniyi‐Jones Moses Sinkala

Chorioamnionitis

10.1016/j.ajog.2006.01.004

Cite

Citations (84)

Heterosexually Transmitted HIV Infection Among African Americans in North Carolina

JAIDS Journal of Acquired Immune Deficiency Syndromes (2006)

Adaora A. Adimora Victor J. Schoenbach Francis Martinson Tamera Coyne‐Beasley Irene A. Doherty

Rates of heterosexually transmitted HIV infection among African Americans in the southeastern United States greatly exceed those for whites.Determine risk factors for heterosexually transmitted HIV infection among African Americans.Population-based case-control study of black men and women, aged 18-61 years, reported to the North Carolina state health department with a recent diagnosis of heterosexually transmitted HIV infection and age- and gender-matched controls randomly selected from the state driver's license file. A lower-risk stratum of respondents was created to identify transmission risks among people who denied high-risk behaviors.Most case subjects reported annual household income < $16,000, history of sexually transmitted diseases, and high-risk behaviors, including crack cocaine use and sex partners who injected drugs or used crack cocaine. However, 27% of case subjects (and 69% of control subjects) denied high-risk sexual partners or behavior. Risk factors for HIV infection in this subset of participants were less than high school education (adjusted odds ratio [OR] 5.0; 95% CI: 2.2, 11.1), recent concern about having enough food for themselves or their family (OR 3.7; 1.5, 8.9), and having a sexual partner who was not monogamous during the relationship with the respondent (OR 2.9; 1.3, 6.4).Although most heterosexually transmitted HIV infection among African Americans in the South is associated with established high-risk characteristics, poverty may be an underlying determinant of these behaviors and a contributor to infection risk even in people who do not have high-risk behaviors.

10.1097/01.qai.0000191382.62070.a5

Cite

Citations (187)

The feasibility of replacement feeding as an HIV prevention method in Lilongwe, Malawi: Results of the BAN Study

The FASEB Journal (2010)

Megan Parker Margaret E. Bentley Linda S. Adair Denise J. Jamieson Sascha Ellingston

International guidelines recommend exclusive breastfeeding (EBF) to 6 months among HIV‐infected mothers choosing to breastfeed, with cessation of BF once replacement feeding is acceptable, feasible, affordable, sustainable and safe. When mothers wean, they are challenged to provide an adequate replacement diet. This study investigates use and acceptability of a peanut‐based ready‐to‐use, micronutrient‐enriched paste (RUF) as a breastmilk substitute when provided to 6–12 mo. old infants of HIV+ mothers, as part of the BAN (Breastfeeding, Antiretroviral, and Nutrition) Study. A sub‐sample of mothers (n=45) was interviewed when their child was 15–16 mo. old. Quantitative and qualitative analyses explored issues related to weaning strategies using RUF from 6 to12 mo. and challenges faced when RUF was no longer provided at 12 mo. Mothers reported 8 strategies used for cessation of BF at 6–7 months including gradual reduction of BF episodes, expressing breastmilk into a cup, and using alternate caregivers. RUF was well accepted by mothers and infants (98%) and incorporated into the traditional infant diet. When RUF was no longer provided, infants stopped accepting the staple maize porridge, particularly among food insecure households. Early BF cessation is a feasible HIV prevention method among this low‐income population in Malawi when supported by the provision of RUF as a breast milk substitute. Grant Funding Source : CDC and the National Institutes of Health, National Institute of Child Health and Human Development (NICHD, 1R03HD057775‐01)

Child Health

10.1096/fasebj.24.1_supplement.94.6

Cite

Citations (0)

Comparative population structure of Plasmodium falciparum circumsporozoite protein NANP repeat lengths in Lilongwe, Malawi

Scientific Reports (2013)

Natalie M. Bowman Seth Congdon Tisungane Mvalo Jaymin C. Patel Verónica Escamilla

Humoral immunity to Plasmodium falciparum circumsporozoite protein is partly mediated by a polymorphic NANP tetra-amino acid repeat. Antibody response to these repeats is the best correlate of protective immunity to the RTS,S malaria vaccine, but few descriptions of the natural variation of these repeats exist. Using capillary electrophoresis to determine the distribution of NANP repeat size polymorphisms among 98 isolates from Lilongwe, Malawi, we characterised the diversity of P. falciparum infection by several ecological indices. Infection by multiple distinct variants was common and 20 distinct repeat sizes were identified. Diversity of P. falciparum appeared greater in children (18 variants) than adults (12 variants). There was evidence of genetic distance between different geographic regions by Nei's Standard Genetic Distance, suggesting parasite populations vary locally. We show that P. falciparum is very diverse with respect to NANP repeat length even on a local level and that diversity appears higher in children.

Circumsporozoite protein

10.1038/srep01990

Cite

Citations (28)

Seroepidemiological survey of hepatitis B and C virus infections in Ghanaian children

Journal of Medical Virology (1996)

Francis Martinson Kristen A. Weigle Isa K. Mushahwar David J. Weber Rachel A. Royce

The seroprevalences of hepatitis B virus (HBV) and hepatitis C virus (HCV) markers were evaluated in a random sample of 803 children attending school in Ashanti-Akim North district in Ghana in order to gain a better understanding of transmission patterns of these viruses, particularly horizontal transmission of HBV. This rural district is typical of 70% of the Ghanaian population. The overall seroprevalence of at least one marker of HBV infection was 61.2%, with rates increasing from 48% to 80% between the ages of 6–18 years (P < 0.001). The overall HBsAg seroprevalence was 15.8%, with the proportion of HBsAg positives amongst those with anti-HBc increasing from 39.3% in 6–7-year-olds to 51.8% in 12–13-year-old. It appears that horizontal transmission during this age period was accompanied by a high rate of HBsAg carriage. Among those infected but not carriers, i.e., those HBsAg negative and anti-HBc positive, >50% lacked detectable levels of anti-HBs, an unusual pattern of convalescent immune response to HBV. The overall seroprevalence of anti-HCV was 5.4% and did not differ significantly by age or gender. Anti-HCV seroprevalence was not associated with the presence of any HBV marker. A better understanding of the unusually high prevalences of HBV and HCV infections demonstrated in this population is likely to influence vaccination and blood transfusion policies and to stimulate further evaluations of these infections and their vehicles of spread in highly endemic regions such as sub-Saharan Africa. © 1996 Wiley-Liss, Inc.

Seroprevalence

Carriage

Hepatitis B

Orthohepadnavirus

10.1002/(sici)1096-9071(199603)48:3<278::aid-jmv11>3.3.co;2-5

Cite

Citations (6)