Djamila Meguellati-Hakkas

Assistance Publique – Hôpitaux de Paris

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Isabelle Stücker

Centre de recherche en Epidémiologie et Santé des Populations

Danièle Luce

Institut de Recherche en Santé, Environnement et Travail

Jean‐Claude Carel

Université Paris Cité

EÉ

Emmanuel Écosse

Université Paris Cité

Florentia Kaguelidou

Sorbonne Paris Cité

Diane Cyr

Université de Versailles Saint-Quentin-en-Yvelines

F Landier

Délégation Paris 7

Grégoire Rey

Centre d'Épidémiologie sur les Causes Médicales de Décès

Sylvie Cénée

Inserm

Luis Guenel

Inserm

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Université Paris Cité

Assistance Publique – Hôpitaux de Paris

Centre de recherche en Epidémiologie et Santé des Populations

Sorbonne Paris Cité

Université Paris-Sud

Hôpital Robert-Debré

Université Paris-Saclay

Université de Versailles Saint-Quentin-en-Yvelines

Santé Publique France

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Long-Term Mortality after Recombinant Growth Hormone Treatment for Isolated Childhood Short Stature: Report of the French SAGhE Study

Jean‐Claude Carel Emmanuel Écosse F Landier Djamila Meguellati-Hakkas Florentia Kaguelidou

Idiopathic short stature

10.1210/endo-meetings.2011.part1.or1.lb-5

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Citations (2)

Lung Cancer Mortality and Occupational Exposure to Asbestos Among Telephone Linemen: A Historical Cohort Study in France

Journal of Occupational and Environmental Medicine (2006)

Djamila Meguellati-Hakkas Diane Cyr Isabelle St cker Jo lle F votte Corinne Pilorget

Objective: The authors studied the mortality by lung cancer in telephone linemen exposed to asbestos at low levels during installation of telephone cables. Methods: Three hundred eight lung cancers deaths were identified in the cohort. Exposure to asbestos and to other occupational carcinogens was assessed using a job-exposure matrix. Results: The relative risk for lung cancer death associated with an estimated exposure of approximately 2 f/cc-years was 2.1 (95% confidence interval = 1.1–4.0) as compared with workers exposed to less than 0.5 f/cc-years. Mean annual exposure or exposure duration were not clearly related to lung cancer. Adjustment for other occupational lung carcinogens did not change this finding. Conclusion: The observed mortality by lung cancer associated with asbestos exposure at low levels is higher than the prediction based on linear downward extrapolations from highly exposed occupational cohorts.

10.1097/01.jom.0000243357.70143.47

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Citations (18)

P42 - Mortalité par cancer du poumon des agents des lignes de France Télécom exposés à l’amiante

Revue d Épidémiologie et de Santé Publique (2005)

Djamila Meguellati-Hakkas Danièle Luce Diane Cyr Isabelle Stücker Luis Guenel

10.1016/s0398-7620(05)84664-4

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Long-Term Mortality after Recombinant Growth Hormone Treatment for Isolated Growth Hormone Deficiency or Childhood Short Stature: Preliminary Report of the French SAGhE Study

The Journal of Clinical Endocrinology & Metabolism (2012)

Jean‐Claude Carel Emmanuel Écosse F Landier Djamila Meguellati-Hakkas Florentia Kaguelidou

Context:Little is known about the long-term health of subjects treated with GH in childhood, and Safety and Appropriateness of Growth hormone treatments in Europe (SAGhE) is a study addressing this question.

Standardized mortality ratio

10.1210/jc.2011-1995

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Étude de la mortalité par cancer des travailleurs de l’industrie routière française exposés aux fumées de bitume

Archives des maladies professionnelles et de médecine du travail/Archives des maladies professionnelles et de l'environnement (2005)

Djamila Meguellati-Hakkas Isabelle Stücker Denis Hémon Sylvie Cénée

10.1016/s1775-8785(05)79061-5

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Rôle des expositions modérées aux HPA et à l'amiante dans la mortalité par cancer du poumon en milieu professionnel

Djamila Meguellati-Hakkas

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B1-5 Étude de la mortalité par cancer des travailleurs de l’industrie routière française exposés aux fumées de bitume

Revue d Épidémiologie et de Santé Publique (2004)

Djamila Meguellati-Hakkas Isabelle Stücker Denis Hémon Sylvie Cénée

10.1016/s0398-7620(04)99130-4

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Authors' Response

Journal of Occupational and Environmental Medicine (2007)

Djamila Meguellati-Hakkas Isabelle Stücker Danièle Luce Pascal Guénel

To the Editor: Following our report of an increased risk of lung cancer related to asbestos exposure in telephone linemen,1 the authors of the above comment draw our attention to the risk of mesothelioma in this occupation, as well as to other possible occupational exposures that may explain elevated risk of respiratory cancers. A mesothelioma register was not set up among French telephone linemen, but deaths from cancer of the pleura can be used as a proxy for studying mortality from mesothelioma. Ten cancers of the pleura occurred in the cohort, leading to a non-statistically significant standardized mortality ratio of 1.2 using the French general population as a reference. This provides only limited evidence of an elevated risk of mesothelioma among French telephone linemen, but the long latency period of the disease after asbestos exposure may require additional years of follow-up in our cohort to detect an elevated risk. Exposure to talc from making telephone cables is suggested by the authors as an additional occupational hazard. As far as we know, however, talc in telephone cables was not used by telephone workers in our cohort before the end of the follow-up period, making our data irrelevant for studying the carcinogenic properties of this exposure. Djamila Meguellati-Hakkas, PhD Isabelle Stucker, PhD Danièle Luce, PhD Pascal Guenel, MD, PhD INSERM Unit 754 and Unit 687 Villejuif FRANCE

Chrysotile

Asbestosis

10.1097/jom.0b013e31804f5ab8

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