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Zhiguo Chen

University of Texas Southwestern Medical Center

15

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340

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Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.

2020 JCI insight
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Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins.

2020 Journal of Clinical Investigation
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Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway

2019 Cancer Discovery
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Overcoming BET Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors

2019 Clinical Cancer Research
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New insights into the neurofibroma tumor cells of origin

2019
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Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

2018
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The role of nerve microenvironment for neurofibroma development

2016 Oncotarget
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Cells of Origin in the Embryonic Nerve Roots for NF1-Associated Plexiform Neurofibroma

2014 Cancer Cell
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BET Bromodomain Inhibition Triggers Apoptosis of NF1-Associated Malignant Peripheral Nerve Sheath Tumors through Bim Induction

2014 Cancer Research
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BET Bromodomain Inhibition Triggers Apoptosis of NF1-associated Malignant Peripheral Nerve Sheath Tumors through Bim Induction

2014 Cell Reports
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Citations (56)