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Xiamei Zhang

Biogen Idec

6

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294

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A small molecule TGF-b signaling inhibitor synergizes with agonistic OX40 antibody to elicit a potent anti-tumor and anti-metastatic response in a breast cancer model

2011 Journal of Immunology
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An orally active small molecule TGF-β receptor I antagonist inhibits the growth of metastatic murine breast cancer

2009 Anticancer Research
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Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy.

2008 Cancer Research
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SM16, an Orally Active TGF-β Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model

2008 Arteriosclerosis, Thrombosis, and Vascular Biology
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The Use of Virtual Screening in ALK5 Kinase Inhibitor Discovery and Validation of Orally Active ALK5 Kinase Inhibitors in Oncology

2008
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A Novel Small-Molecule Inhibitor of Transforming Growth Factor β Type I Receptor Kinase (SM16) Inhibits Murine Mesothelioma Tumor Growth In vivo and Prevents Tumor Recurrence after Surgical Resection

2007 Cancer Research
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