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Bin He

Bristol-Myers Squibb

13

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Synthesis and structure–activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)

2014 Bioorganic & Medicinal Chemistry Letters
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Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1).

2011 Bioorganic & Medicinal Chemistry Letters
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Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).

2011 Bioorganic & Medicinal Chemistry Letters
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Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation

2008 Protein Science
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11-bêta-hydroxystéroïde déshydrogénase de type 1

2008
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Quinolines as extremely potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction

2004 Bioorganic & Medicinal Chemistry Letters
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Substituted pyrazolopyridopyridazines as orally bioavailable potent and selective PDE5 inhibitors: potential agents for treatment of erectile dysfunction.

2003 Journal of Medicinal Chemistry
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Substituted Pyrazolopyridines as Potent and Selective PDE5 Inhibitors: Potential Agents for Treatment of Erectile Dysfunction

2001 Journal of Medicinal Chemistry
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The discovery of novel, potent and selective PDE5 inhibitors

2001 Bioorganic & Medicinal Chemistry Letters
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The Discovery of Novel, Potent and Selective PDE5 Inhibitors.

2001 ChemInform
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