author-photo

Christine Lambert-van der Brempt

AstraZeneca

24

Papers

866

Citations

Citation Trend

Filter By

Papers (19) Sort By

Journal Conference Others

Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors

2017 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (5)
Abstract 2830: Discovery of AZD8835, a potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of PIK3CA-dependent cancers

2015 Cancer Research
Show All
- Source
- Cite
- Save
Citations (1)
Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold.

2015 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (8)
Discovery of 9-(1-anilinoethyl)-2-morpholino-4-oxo-pyrido[1,2-a]pyrimidine-7-carboxamides as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours

2014 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (16)
Discovery of AZD8931, an Equipotent, Reversible Inhibitor of Signaling by EGFR, HER2, and HER3 Receptors.

2013 ACS Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (25)
Facile, Diversity-Orientated One-Pot Synthesis of Ethyl 1,5-Disubstituted-1H-1,2,4-triazole-3-carboxylates.

2013 ChemInform
Show All
- Source
- Cite
- Save
Citations (0)
Discovery of new quinoline ether inhibitors with high affinity and selectivity for PDGFR tyrosine kinases.

2012 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (7)
Structure-activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: part 1.

2012 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (7)
Facile, diversity-orientated one-pot synthesis of ethyl 1,5-disubstituted-1H-1,2,4-triazole-3-carboxylates

2012 Tetrahedron Letters
Show All
- Source
- Cite
- Save
Citations (11)
Efficient three-step one-pot synthesis of a novel 2,3,5-substituted pyrazine library.

2011 ACS Combinatorial Science
Show All
- Source
- Cite
- Save
Citations (12)