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Christine Gelin

Novartis

5

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74

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Complement factor D in complex with the inhibitor (S)-2-(2-((3'-(1-amino-2-hydroxyethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)acetic acid

2019
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Design, synthesis and pre-clinical characterization of selective Factor D inhibitors targeting the alternative complement pathway.

2019 Journal of Medicinal Chemistry
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4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate

2017 Journal of Medicinal Chemistry
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