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Adrian P. Kells

University of California, San Francisco

45

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Data-driven evolution of neurosurgical gene therapy delivery in Parkinson's disease

2020 Journal of Neurology, Neurosurgery, and Psychiatry
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GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop.

2020 Journal of Parkinson's disease
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Safety Assessment of AAV2-hGDNF Administered Via Intracerebral Injection in Rats for Treatment of Parkinson's Disease.

2020 International Journal of Toxicology
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Development of a novel frameless skull-mounted ball-joint guide array for use in image-guided neurosurgery

2019 Journal of Neurosurgery
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PD-1102: A Phase 1 study of VY-AADC01 Administered Using a Posterior Approach in Patients with Parkinson’s Disease and Motor Fluctuations (P1.8-017)

2019 Neurology
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Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus

2018 Journal of Neuroscience Methods
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Slow AAV2 clearance from the brain of nonhuman primates and anti-capsid immune response

2016 Gene Therapy
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647. Repeated Infusion of AAV2-hAADC Into the Thalamus of Non-Human Primates: Effect of Anti-AAV2 Antibodies on Transgene Expression

2015 Molecular Therapy
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Glial cell line-derived neurotrophic factor (GDNF) is an endogenous protector in the mesolimbic system against excessive alcohol consumption and relapse.

2015 Addiction Biology
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AAV9-mediated Expression of a Non-self Protein in Nonhuman Primate Central Nervous System Triggers Widespread Neuroinflammation Driven by Antigen-presenting Cell Transduction

2014 Molecular Therapy
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Citations (92)