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Katrina W. Lexa

University of Michigan

30

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Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.

2021 Cell
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Application of Machine Learning and Reaction Optimization for the Iterative Improvement of Enantioselectivity of Cinchona-Derived Phase Transfer Catalysts

2021 Organic Process Research & Development
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Ticks Resist Skin Commensals with Immune Factor of Bacterial Origin.

2020 Cell
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Combining traditional 2D and modern physical organic-derived descriptors to predict enhanced enantioselectivity for the key aza-Michael conjugate addition in the synthesis of Prevymis™ (letermovir)

2018 Chemical Science
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Asymmetric Hydrogen Bonding Catalysis for the Synthesis of Dihydroquinazoline-Containing Antiviral, Letermovir

2017 Journal of the American Chemical Society
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Unusual (+/-)-electrospray ionization induced fragmentation: Structural elucidation of an in-process synthetic intermediate of doravirine (MK-1439) using liquid chromatography/high-resolution tandem mass spectrometry and two-dimensional nuclear magnetic r: Unusual MS fragmentation of a doravirine impurity

2017 Rapid Communications in Mass Spectrometry
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Unusual (+/-)-electrospray ionization induced fragmentation: Structural elucidation of an in-process synthetic intermediate of doravirine (MK-1439) using liquid chromatography/high-resolution tandem mass spectrometry and two-dimensional nuclear magnetic r: Unusual MS fragmentation of a doravirine impurity

2017 Rapid Communications in Mass Spectrometry
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A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions

2017 Chemical Science
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Mechanistic Study of the Gas-Phase In-Source Hofmann Elimination of Doubly Quaternized Cinchona-Alkaloid Based Phase-Transfer Catalysts by (+)-Electrospray Ionization/Tandem Mass Spectrometry

2017 Journal of the American Society for Mass Spectrometry
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Exhaustive Conformational Sampling of Complex Fused Ring Macrocycles Using Inverse Kinematics

2016 Journal of Chemical Theory and Computation
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Citations (38)