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Simon Giroux

Vertex Pharmaceuticals

14

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98

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Discovery of Potent, Selective Triazolothiadiazole-Containing c-Met Inhibitors

2021 ACS Medicinal Chemistry Letters
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Application of a Dual Catalytic Nickel/Iridium-Based Photoredox Reaction to Synthesize 2-Alkyl-N-Arylindoles in a Continuous Flow

2020 Journal of Organic Chemistry
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ROCK Inhibitors 4: Structure-Activity Relationship Studies of 7-Azaindole-Based Rho Kinase (ROCK) Inhibitors

2020 Bioorganic & Medicinal Chemistry Letters
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C–H Functionalization of Heteroarenes Using Unactivated Alkyl Halides through Visible-Light Photoredox Catalysis under Basic Conditions

2018 Journal of Organic Chemistry
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Benzimidazole-containing HCV NS5A inhibitors: effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency.

2015 Bioorganic & Medicinal Chemistry Letters
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Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores.

2015 Bioorganic & Medicinal Chemistry Letters
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Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors.

2014 ACS Medicinal Chemistry Letters
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Overcoming acquired resistance to kinase inhibition: the cases of EGFR, ALK and BRAF.

2013 Bioorganic & Medicinal Chemistry Letters
- Simon Giroux
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Production processes gyrase inhibitors and topoisomerase IV

2012
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Selenium(IV) Oxide

2007
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Citations (3)