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Ruihuan Chen

Genentech

21

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3519

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A Small Vimentin-Binding Molecule Blocks Cancer Exosome Release and Reduces Cancer Cell Mobility.

2021 Frontiers in Pharmacology
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A vimentin-targeting oral compound with host-directed antiviral and anti-inflammatory actions addresses multiple features of COVID-19 and related diseases

2021 bioRxiv
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Abstract P35: Targeting vimentin impacts multiple cellular processes, blocks the spike protein-ACE2-mediated pseudoviral infection in vitro and reduces the symptom and lung injury in aged mice with mouse-adapted SARS-CoV-2 infection in vivo

2021 Clinical Cancer Research
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Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma

2014 Proceedings of the National Academy of Sciences of the United States of America
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Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation

2013 Neuro-oncology
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A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

2010 Cancer Cell
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Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma.

2007 Proceedings of the National Academy of Sciences of the United States of America
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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

2006 Cancer Cell
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Derives d'isoindigo, d'indigo et d'indirubine et utilisation de ceux-ci dans le traitement de cancer

2002
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Isoindigo derivatives, indigo and indirubin and its use in cancer treatment.

2002
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