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Masakuni Kurono
Masakuni Kurono
Receptor
Chemistry
Biochemistry
Stereochemistry
Agonist
5
Papers
77
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Discovery of a 1-Methyl-3,4-dihydronaphthalene-Based Sphingosine-1-Phosphate (S1P) Receptor Agonist Ceralifimod (ONO-4641). A S1P1 and S1P5 Selective Agonist for the Treatment of Autoimmune Diseases
2017
Journal of Medicinal Chemistry
Haruto Kurata
Kensuke Kusumi
Kazuhiro Otsuki
Ryo Suzuki
Masakuni Kurono
Takaki Komiya
Hiroshi Hagiya
Hirotaka Mizuno
Hiroki Shioya
Takeji Ono
Yuka Takada
Tatsuo Maeda
Norikazu Matsunaga
Tetsu Kondo
Sachiko Tominaga
Ken-ici Nunoya
Hidekazu Kiyoshi
Masaharu Komeno
Shinji Nakade
Hiromu Habashita
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Citations (9)
Efficacy and immunomodulatory actions of ONO-4641, a novel selective agonist for sphingosine 1-phosphate receptors 1 and 5, in preclinical models of multiple sclerosis
2013
Clinical and Experimental Immunology
Takaki Komiya
K. Sato
Hiroki Shioya
Y. Inagaki
Hiroshi Hagiya
R. Kozaki
Masamichi Imai
Yuka Takada
Tatsuo Maeda
Haruto Kurata
Masakuni Kurono
Ryo Suzuki
Kazuhiro Otsuki
Hiromu Habashita
Shinji Nakade
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Citations (41)
Structure–activity relationship studies of S1P agonists with a dihydronaphthalene scaffold
2012
Bioorganic & Medicinal Chemistry Letters
Haruto Kurata
Kensuke Kusumi
Kazuhiro Otsuki
Ryo Suzuki
Masakuni Kurono
Natsuko Tokuda
Yuka Takada
Hiroki Shioya
Hirotaka Mizuno
Takaki Komiya
Takeji Ono
Hiroshi Hagiya
Masashi Minami
Shinji Nakade
Hiromu Habashita
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Citations (12)
Discovery of S1P agonists with a dihydronaphthalene scaffold.
2011
Bioorganic & Medicinal Chemistry Letters
Haruto Kurata
Kensuke Kusumi
Kazuhiro Otsuki
Ryo Suzuki
Masakuni Kurono
Yuka Takada
Hiroki Shioya
Takaki Komiya
Hirotaka Mizuno
Takeji Ono
Hiroshi Hagiya
Masashi Minami
Shinji Nakade
Hiromu Habashita
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Citations (8)
Structure–activity relationship studies of sphingosine-1-phosphate receptor agonists with N-cinnamyl-β-alanine moiety
2011
Bioorganic & Medicinal Chemistry Letters
Haruto Kurata
Kazuhiro Otsuki
Kensuke Kusumi
Masakuni Kurono
Masahiko Terakado
Takuya Seko
Hirotaka Mizuno
Takeji Ono
Hiroshi Hagiya
Masashi Minami
Shinji Nakade
Hiromu Habashita
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Citations (7)
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