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Carla Schmidt

University of Groningen

9

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Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity

2010 Blood
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The novel type II CD20 antibody GA101 mediated superior B cell depletion in whole blood from healthy volunteers and B-CLL patients.

2009
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Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis.

2009 British Journal of Cancer
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Novel third generation humanized type IICD20 antibody with superior direct cell death induction and glycoengineered Fc region for enhanced ADCC induction

2007 Molecular Cancer Therapeutics
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GA101: A humanized third generation type II CD20 antibody with superior cell death induction and glycoengineered Fc region for enhanced ADCC

2007 Cancer Research
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Characterization of Monoclonal Antibodies to Novikoff Hepatoma Cytokeratin Antigen p39

1984 Cancer Research
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