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Paul A. Dickinson

AstraZeneca
Cardiff University

54

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230MO First in human, modular study of samuraciclib (CT7001), a first-in-class, oral, selective inhibitor of CDK7, in patients with advanced solid malignancies

2021 Annals of Oncology
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Exploring a model-based analysis of patient derived xenograft studies in oncology drug development

2021 PeerJ
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Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report.

2020 Journal of Pharmaceutical Sciences
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Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products

2020 Aaps Journal
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The effect of itraconazole and rifampicin on the pharmacokinetics of osimertinib

2018 British Journal of Clinical Pharmacology
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The Effect of Food or Omeprazole on the Pharmacokinetics of Osimertinib in Patients With Non-Small-Cell Lung Cancer and in Healthy Volunteers

2018 The Journal of Clinical Pharmacology
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Chapter 15 Clinically Relevant Dissolution for Low-Solubility Immediate-Release Products

2017
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Effect of itraconazole or rifampicin on the pharmacokinetics (PK) of osimertinib (AZD9291).

2016 Journal of Clinical Oncology
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Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor

2016 Drug Metabolism and Disposition
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Systems Pharmacology Modeling of Prostate-Specific Antigen in Patients With Prostate Cancer Treated With an Androgen Receptor Antagonist and Down-Regulator

2016
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