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Simon Kirby

Pfizer

24

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391

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Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis

2019 Pharmacology Research & Perspectives
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Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort

2019 Hepatology
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Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy

2018 Pain
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Designing Proof-of-Concept Trials with Desired Characteristics

2017
- Christy Chuang-Stein
- Simon Kirby
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The Parallel Between Clinical Trials and Diagnostic Tests

2017
- Christy Chuang-Stein
- Simon Kirby
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A Frequentist Decision-Making Framework

2017
- Christy Chuang-Stein
- Simon Kirby
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Quantitative Decisions in Drug Development

2017
- Christy Chuang-Stein
- Simon Kirby
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Incorporating Information from Completed Trials in Future Trial Planning

2017
- Christy Chuang-Stein
- Simon Kirby
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Choosing Metrics Appropriate for Different Stages of Drug Development

2017
- Christy Chuang-Stein
- Simon Kirby
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Designing Dose-Response Studies with Desired Characteristics

2017
- Christy Chuang-Stein
- Simon Kirby
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