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Andy Billinton

GlaxoSmithKline

21

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Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain.

2019 Pain
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Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP 4 receptor partial agonist for the treatment of pain

2018 Bioorganic & Medicinal Chemistry Letters
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MEDI1814, A HIGH-AFFINITY ANTIBODY DIRECTED TO THE C-TERMINUS OF AβX-42, ABROGATES SYNAPTIC PLASTICITY DISRUPTION CAUSED BY SYNTHETIC OR AD BRAIN-DERIVED Aβ SOLUBLE ASSEMBLIES IN VIVO

2017 Alzheimers & Dementia
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EVALUATION OF SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF MEDI1814, A BETA-AMYLOID 42 (Aβ42)-SPECIFIC ANTIBODY, IN PATIENTS WITH MILD-MODERATE ALZHEIMER'S DISEASE

2017 Alzheimers & Dementia
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PRECLINICAL DISCOVERY AND DEVELOPMENT OF MEDI1814, A MONOCLONAL ANTIBODY SELECTIVELY TARGETING BETA-AMYLOID 42 (Aβ42)

2017 Alzheimers & Dementia
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Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor.

2010 Bioorganic & Medicinal Chemistry Letters
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Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X(7) receptor.

2010 Bioorganic & Medicinal Chemistry Letters
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Human dental pulp as a source of native functional nociceptor pharmacology

2009 Pain
- Andy Billinton
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434 ANTINOCICEPTIVE EFFECTS OF A SELECTIVE ERBETA AGONIST THROUGH MODULATION OF THE ENDOGENOUS OPIOID SYSTEM

2009 European Journal of Pain
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Activation of the α7-Nicotinic Acetylcholine Receptor Reverses Complete Freund Adjuvant–Induced Mechanical Hyperalgesia in the Rat Via a Central Site of Action

2008 The Journal of Pain
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