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Amy G. Aslamkhan

National Institutes of Health

9

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Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development that informs Chemically Reactive Metabolite formation and Potential for Drug Induced Liver Injury.

2020 Toxicological Sciences
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AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated with Tumorigenic Risks in Rats.

2019 Toxicological Sciences
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The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3

2006 American Journal of Physiology-regulatory Integrative and Comparative Physiology
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Interactions of tetrapentylammonium (TPeA) with organic anion transporter 3 (Oat3) in rat choroid plexus (CP) and kidney slices

2006 The FASEB Journal
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Human organic anion transporter 1 mediates cellular uptake of cysteine-S conjugates of inorganic mercury.

2004 Kidney International
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Delayed DMSO Administration Protects the Kidney from Mercuric Chloride-Induced Injury

2004 Journal of The American Society of Nephrology
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Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells

2003 Molecular Pharmacology
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Stoichiometry of organic anion/dicarboxylate exchange in membrane vesicles from rat renal cortex and hOAT1-expressing cells

2003 American Journal of Physiology-renal Physiology
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