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Patrik Zeyen
Patrik Zeyen
Martin Luther University of Halle-Wittenberg
Chemistry
HDAC8
Biochemistry
Docking (dog)
Schistosoma mansoni
5
Papers
36
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Binding Free Energy (BFE) Calculations and Quantitative Structure-Activity Relationship (QSAR) Analysis of Schistosoma mansoni Histone Deacetylase 8 (smHDAC8) Inhibitors.
2021
Molecules
Conrad V. Simoben
Ehab Ghazy
Patrik Zeyen
Salma Darwish
Matthias Schmidt
Christophe Romier
Dina Robaa
Wolfgang Sippl
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Citations (1)
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis
2021
European Journal of Medicinal Chemistry
Ehab Ghazy
Tino Heimburg
Julien Lancelot
Patrik Zeyen
Karin Schmidtkunz
Anne Truhn
Salma Darwish
Conrad V. Simoben
Tajith B. Shaik
Frank Erdmann
Matthias Schmidt
Dina Robaa
Christophe Romier
Manfred Jung
Raymond J. Pierce
Wolfgang Sippl
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Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1
2020
European Journal of Medicinal Chemistry
Ehab Ghazy
Patrik Zeyen
Daniel Herp
Martin Hügle
Karin Schmidtkunz
Frank Erdmann
Dina Robaa
Matthias Schmidt
Elizabeth R. Morales
Christophe Romier
Stefan Günther
Manfred Jung
Wolfgang Sippl
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Citations (6)
Structure-Based Design and Biological Characterization of Selective Histone Deacetylase 8 (HDAC8) Inhibitors with Anti-Neuroblastoma Activity
2017
Journal of Medicinal Chemistry
Tino Heimburg
Fiona R. Kolbinger
Patrik Zeyen
Ehab Ghazy
Daniel Herp
Karin Schmidtkunz
Jelena Melesina
Tajith B. Shaik
Frank Erdmann
Matthias Schmidt
Christophe Romier
Dina Robaa
Olaf Witt
Ina Oehme
Manfred Jung
Wolfgang Sippl
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Citations (28)
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