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Paul J. Boersema

ETH Zurich

37

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3246

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Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ

2021 Cell
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Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity

2019 Cell systems
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TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates

2019 Nature Neuroscience
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Distinct TDP-43 aggregate features and toxicity stratify FTD patients

2019
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Phosphorylation of nuclear Tau is modulated by distinct cellular pathways

2018 Scientific Reports
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Chemical stresses fail to mimic the unfolded protein response resulting from luminal load with unfolded polypeptides

2018 Journal of Biological Chemistry
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Systematic proteome and proteostasis profiling in human Trisomy 21 fibroblast cells

2017 Nature Communications
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Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability

2017 Science
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Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry

2017 Nature Protocols
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Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis

2017 Molecular Systems Biology
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Citations (72)