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Feng Zhao

Harvard University

13

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1224

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An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition

2016 PLOS ONE
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Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas.

2016 Journal of Medicinal Chemistry
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Mass Spectrometric Quantification of Histone Post-translational Modifications by a Hybrid Chemical Labeling Method

2015 Molecular & Cellular Proteomics
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Abstract 5526: Inhibition of the histone methyl transferase EZH2 causes viability defects in multiple myeloma

2014 Cancer Research
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EZH2 Inhibitor Efficacy in Non-Hodgkin’s Lymphoma Does Not Require Suppression of H3K27 Monomethylation

2014 Chemistry & Biology
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Identification of EZH2 and EZH1 Small Molecule Inhibitors with Selective Impact on Diffuse Large B Cell Lymphoma Cell Growth

2013 Chemistry & Biology
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PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with EGFR and ERBB2 Mutations that Are Resistant to Gefitinib

2007 Cancer Research
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