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David A. Matthews

University of Bristol

114

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5079

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Structural basis for cell-type specific evolution of viral fitness by SARS-CoV-2

2021 bioRxiv
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Structure and mechanism of SARS-CoV-2 Spike N679-V687 deletion variant elucidate cell-type specific evolution of viral fitness

2021 bioRxiv
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TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction

2021 PLOS Pathogens
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The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets.

2021 Nature microbiology
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Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans

2021
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Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care.

2021 Genome Medicine
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Citations (5)
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction

2021 bioRxiv
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Chronic SARS-CoV-2 infection and viral evolution in a hypogammaglobulinaemic individual.

2021
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Variation around the dominant viral genome sequence contributes to viral load and outcome in patients with Ebola virus disease.

2020 Genome Biology
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The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells.

2020 bioRxiv
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Citations (66)