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Fabien Gautier

University of Nantes

41

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Synthesis and biological studies of new piperidino-1,2,3-triazole hybrids with 3-aryl isoxazole side chains.

2021 Bioorganic & Medicinal Chemistry Letters
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Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model

2020 Cancer and Metabolism
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STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment

2020 Nature Communications
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STING-dependent paracriny shapes apoptotic priming of breast tumors in response to anti-mitotic treatment. Lohard et al.

2019
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Interactions between cancer-associated fibroblasts and tumor cells promote MCL-1 dependency in estrogen receptor-positive breast cancers

2019 Oncogene
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Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode

2018 European Journal of Medicinal Chemistry
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Abstract 3996: Pyridoclax and its derivatives from oligopyridine family directly inhibit Mcl-1 and exert potent antitumor effects on ovarian cancer in vitro and in vivo

2018 Cancer Research
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Synthesis and cytotoxicity studies of newly designed benzyl-hydroquinone derivatives

2018 Medicinal Chemistry Research
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Efficient mitochondrial glutamine targeting prevails over glioblastoma metabolic plasticity.

2017 Clinical Cancer Research
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E2F1 interacts with BCL‐xL and regulates its subcellular localization dynamics to trigger cell death

2017 EMBO Reports
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