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Senthil K. Radhakrishnan

Virginia Commonwealth University

11

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165

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Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity

2020 International Journal of Molecular Sciences
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BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response

2020
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Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration.

2020 Molecular Biology of the Cell
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Transcriptional Regulation of the Proteasome: Implications for Cancer Therapy

2020 The FASEB Journal
- Senthil K. Radhakrishnan
- Janakiram R. Vangala
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Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex

2019 Journal of Biological Chemistry
- Janakiram R. Vangala
- Senthil K. Radhakrishnan
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Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress

2019 Biochimica et Biophysica Acta
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QPI Allows in vitro Drug Screening of Triple Negative Breast Cancer PDX Tumors and Fine Needle Biopsies

2019 Frontiers in Physics
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Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity

2017 ACS central science
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Nrf1 can be processed and activated in a proteasome-independent manner

2016 Current Biology
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