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Alexandre L'Heureux

Bristol-Myers Squibb

20

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349

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Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1-(2-(1′-Neopentylspiro[indoline-3,4′-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea, a Potent, Selective, and Bioavailable P2Y1 Antagonist

2013 Journal of Medicinal Chemistry
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New azole antagonists with high affinity for the P2Y1 receptor

2013 Bioorganic & Medicinal Chemistry Letters
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Aminodifluorosulfinium Tetrafluoroborate Salts as Stable and Crystalline Deoxofluorinating Reagents.

2010 ChemInform
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Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor.

2008 Bioorganic & Medicinal Chemistry Letters
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(S,E)-N-[1-(3-Heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity

2005 Bioorganic & Medicinal Chemistry Letters
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Concise and Efficient Synthesis of 4-Fluoro-1H-pyrrolo[2,3-b]pyridine.

2004 ChemInform
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Synthesis of functionalized 7-azaindoles via directed ortho-metalations ☆

2004 Tetrahedron Letters
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Synthesis of functionalized 7-azaindoles via directed ortho-metalations ☆

2004 Tetrahedron Letters
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Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers

2004 Journal of Medicinal Chemistry
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Inhibiteurs de l'azaindole kinase

2003
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