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Antonio P. Silva

Novartis

15

Papers

415

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Phase 1/1b dose escalation and expansion study of BEZ235, a dual PI3K/mTOR inhibitor, in patients with advanced solid tumors including patients with advanced breast cancer

2018 Cancer Chemotherapy and Pharmacology
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A first-in-human phase I study of the anti-PD-1 antibody PDR001 in patients with advanced solid tumors.

2016 Journal of Clinical Oncology
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SOM230: a new therapeutic modality for Cushing's disease.

2014 Chimia
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366 Phase I Dose-escalation Study of the Oral Dual MTOR/PI3K Inhibitor BEZ235, Solid Dispersion System (SDS) Sachet Formulation, in Patients with Advanced Solid Tumors

2012 European Journal of Cancer
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First-in-human phase I study of the oral PI3K inhibitor BEZ235 in patients (pts) with advanced solid tumors.

2010 Journal of Clinical Oncology
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Abstract P6-15-07: A Dose-Escalation Study with a Special Drug Delivery System (SDS) of BEZ235, a Novel Dual PI3K/mTOR Inhibitor, in Patients with Metastatic/Advanced Solid Tumors

2010 Cancer Research
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MEDI 234-New perspectives on the medicinal chemistry of the somatostatin receptor agonist SOM230

2007
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SOM230 inhibits insulin-like growth factor-I action in mammary gland development by pituitary independent mechanism : Mediated through somatostatin subtype receptor 3?

2006 Molecular Endocrinology
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Regulation of ghrelin secretion by somatostatin analogs in rats

2005 European Journal of Endocrinology
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Regulation of CRH-induced secretion of ACTH and corticosterone by SOM230 in rats

2005 European Journal of Endocrinology
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Citations (49)