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Dayong Zhai

Sanford-Burnham Institute for Medical Research

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Abstract 1469: TPX-0131, a potent inhibitor of wild type ALK and a broad spectrum of both single and compound ALK resistance mutations

2021
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Abstract 5226: TPX-0131: A next generation macrocyclic ALK inhibitor that overcomes ALK resistant mutations refractory to current approved ALK inhibitors

2020
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Repotrectinib increases KRAS-G12C inhibitor effectiveness via simultaneous inhibition of SRC, FAK, and JAK2

2020 European Journal of Cancer
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Abstract 1957: Repotrectinib increases effectiveness of MEK inhibitor trametinib inKRASmutant cancer modelsviasimultaneous SRC/FAK/JAK2 inhibition

2020
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Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling

2019 Cancer Research
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Abstract 1325: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses

2019 Cancer Research
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Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins:

2014 Journal of Biomolecular Screening
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The Point of No Return; 3D Structure of Bax-Mediated Pores in Membrane Bilayers

2014 Biophysical Journal
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Table 10, Structure Activity Relationship (SAR) Elucidation in 3B-17B

2013
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Figure 8, ML258 reverses the Bcl-B dependent blockade of Bim-induced leakage in isolated mitochondria

2013
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