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Christopher Lepsy

Pfizer

17

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314

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Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study

2021 Clinical Gastroenterology and Hepatology
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Antitumor Necrosis Factor-like Ligand 1A Therapy Targets Tissue Inflammation and Fibrosis Pathways and Reduces Gut Pathobionts in Ulcerative Colitis.

2021 Inflammatory Bowel Diseases
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DOP72 Safety, tolerability and efficacy of anti-TL1A antibody PF-06480605 in treatment of ulcerative colitis: The open-label, multicentre, Phase 2a TUSCANY study

2020 Journal of Crohns & Colitis
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Fit-for-Purpose Validation and Establishment of Assay Acceptance and Reporting Criteria of Dendritic Cell Activation Assay Contributing to the Assessment of Immunogenicity Risk.

2020 Aaps Journal
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Anti-drug Antibody Assay Conditions Significantly Impact Assay Screen and Confirmatory Cut-Points

2019 Aaps Journal
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First‐in‐human, randomized dose‐escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of PF‐06480605 in healthy subjects

2019 British Journal of Clinical Pharmacology
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Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis

2018 Inflammatory Bowel Diseases
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Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation.

2017 British Journal of Pharmacology
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Physiologically Relevant Binding Affinity Quantification of Monoclonal Antibody PF‐00547659 to MAdCAM for In Vitro In Vivo Correlation

2016 British Journal of Pharmacology
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The Development and Validation of a Computational Model to Predict Rat Liver Microsomal Clearance

2009 Journal of Pharmaceutical Sciences
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