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Tatsuya Tamura

Chugai Pharmaceutical Co.

33

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3107

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Change of free volume in hydrogenated DLC film by the irradiation of soft X-rays

2021 The Japan Society of Applied Physics
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Optimization of PTH/PTHrP Hybrid Peptides to Derive a Long‐Acting PTH Analog (LA‐PTH)

2020
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Lead Optimization and Avoidance of Reactive Metabolite Leading to PCO371, a Potent, Selective and Orally Available Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist

2020 Journal of Medicinal Chemistry
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Development of a Novel Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist (CH5447240), a Potent and Orally Available Small-Molecule for Treatment of Hypoparathyroidism

2018 Journal of Medicinal Chemistry
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Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism.

2016 Nature Communications
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The Optimal Duration of PTH(1–34) Infusion Is One Hour per Day to Increase Bone Mass in Rats

2016 Biological & Pharmaceutical Bulletin
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Novel hyaluronic acid-methotrexate conjugate suppresses joint inflammation in the rat knee: efficacy and safety evaluation in two rat arthritis models.

2016 Arthritis Research & Therapy
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Long-Term Treatment with Eldecalcitol (1α, 25-Dihydroxy-2β- (3-hydroxypropyloxy) Vitamin D3) Suppresses Bone Turnover and Leads to Prevention of Bone Loss and Bone Fragility in Ovariectomized Rats

2015 Calcified Tissue International
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Synthesis and optimization of hyaluronic acid-methotrexate conjugates to maximize benefit in the treatment of osteoarthritis.

2010 Bioorganic & Medicinal Chemistry
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New resorption assay with mouse osteoclast‐like multinucleated cells formed in vitro

2009 Journal of Bone and Mineral Research
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Citations (86)