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Ningzhe Zhang

Buck Institute for Research on Aging

17

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941

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FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase

2020 Aging Cell
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Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington’s Disease

2019 Journal of Huntington's disease
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Using Genome Engineering to Understand Huntington’s Disease

2017
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KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

2017 Proceedings of the National Academy of Sciences of the United States of America
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Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo

2015 Journal of Biological Chemistry
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Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells

2015 Stem cell reports
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Polyglutamine Disease Modeling: Epitope Based Screen for Homologous Recombination using CRISPR/Cas9 System

2014 PLOS Currents
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UNDERSTANDING THE PATHWAYS THAT LEAD TO NERVE CELL DEATH IN HUNTINGTON’S DISEASE

2014 Free Radical Biology and Medicine
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Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells

2012 Cell Stem Cell
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Responses of Human Embryonic Stem Cells and Their Differentiated Progeny to Ionizing Radiation

2012 Biochemical and Biophysical Research Communications
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Citations (24)