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Axel Schambach

Hannover Medical School
Boston Children's Hospital

406

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Reprogramming enriches for somatic cell clones with small scale mutations in cancer-associated genes.

2021 Molecular Therapy
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Efficient in vivo genome editing mediated by stem cells-derived extracellular vesicles carrying designer nucleases

2021 bioRxiv
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Pulmonary transplantation of alpha-1 antitrypsin (AAT)-transgenic macrophages provides a source of functional human AAT in vivo.

2021 Gene Therapy
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971 NK cell-mediated eradication of ovarian cancer cells with a novel chimeric antigen receptor directed against CD44

2021
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Pre-clinical optimisation and safety studies of a new lentiviral gene therapy for p47phox-deficient chronic granulomatous disease.

2021 Human Gene Therapy
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Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning.

2021 Molecular Therapy
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Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease.

2021 PLOS ONE
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Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages.

2021 Journal of Personalized Medicine
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Proceedings From the First International Workshop at Sidra Medicine: “Engineered Immune Cells in Cancer Immunotherapy (EICCI): From Discovery to Off-the-Shelf Development”, 15th–16th February 2019, Doha, Qatar

2021 Frontiers in Immunology
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Conditionally immortalised leukaemia initiating cells co-expressing Hoxa9/Meis1 demonstrate microenvironmental adaptation properties ex vivo while maintaining myelomonocytic memory.

2021 Scientific Reports
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