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Xavier Gómez-Santacana

Spanish National Research Council

11

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Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.

2021 Cell Reports
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El nacimiento de la fotofarmacología

2019
- Xavier Rovira Algans
- Xavier Gómez-Santacana
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Optical activation of endogenous metabotropic glutamate receptor 4 (mGlu 4 ) in the amygdala dynamically regulates symptoms associated with persistent inflammatory pain

2018 Molecular Psychiatry
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Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation.

2017 European Journal of Medicinal Chemistry
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Computational Analysis of Negative and Positive Allosteric Modulator Binding and Function in Metabotropic Glutamate Receptor 5 (In)Activation

2014 Journal of Chemical Information and Modeling
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A double effect molecular switch leads to a novel potent negative allosteric modulator of metabotropic glutamate receptor 5

2014 MedChemComm
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An allosteric modulator to control endogenous G protein-coupled receptors with light

2014 Nature Chemical Biology
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Citations (94)