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D. Sim
D. Sim
Bayer HealthCare Pharmaceuticals
Medicine
Immunology
Von Willebrand factor
Thrombin
In vivo
4
Papers
48
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Noncovalent stabilization of the factor VIII A2 domain enhances efficacy in hemophilia A mouse vascular injury models
2015
Blood
Lilley Leong
D. Sim
Chandra Patel
Katherine Tran
Perry Liu
Elena Ho
Thomas Thompson
Peter Kretschmer
Hironao Wakabayashi
Philip J. Fay
John E. Murphy
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Citations (7)
Reduced Polyethylene Glycol-Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective Peg Steric Modulation without Affecting Potency
2014
Blood
Eric Blasko
Lilley Leong
D. Sim
L. Tang
Elena Ho
Jim Wu
Katalin Zsofia Kauser
Babu Subramanyam
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Citations (2)
Glycoengineered factor IX variants with improved pharmacokinetics and subcutaneous efficacy
2013
Journal of Thrombosis and Haemostasis
Alan R. Brooks
D. Sim
U. Gritzan
Chandra Patel
E. Blasko
R. I. Feldman
L. Tang
Elena Ho
Xiao-Yan Zhao
H. Apeler
John E. Murphy
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Citations (13)
von Willebrand factor contributes to longer half-life of PEGylated factor VIII in vivo
2013
Haemophilia
L. Tang
L. Leong
D. Sim
Elena Ho
J.-M. Gu
D. Schneider
R. I. Feldman
F. Monteclaro
Haiyan Jiang
John E. Murphy
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Citations (26)
1