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Pamela Sheffels

University of Washington

23

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1064

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Role of CYP2B6 in Stereoselective Human Methadone Metabolism

2008 Anesthesiology
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Enantiomeric Metabolic Interactions and Stereoselective Human Methadone Metabolism

2007 Journal of Pharmacology and Experimental Therapeutics
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Influence of CYP3A5 Genotype on the Pharmacokinetics and Pharmacodynamics of the Cytochrome P4503A Probes Alfentanil and Midazolam

2007 Clinical Pharmacology & Therapeutics
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New Insights into the Mechanism of Methoxyflurane Nephrotoxicity and Implications for Anesthetic Development (Part 1)

2006 Anesthesiology
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Pharmacogenetic Determinants of Human Liver Microsomal Alfentanil Metabolism and the Role of Cytochrome P450 3A5

2005 Anesthesiology
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Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity.

2005 The Journal of Clinical Pharmacology
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Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.

2004 Clinical Pharmacology & Therapeutics
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Bioavailabilities of rectal and oral methadone in healthy subjects.

2004 British Journal of Clinical Pharmacology
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Miosis following intravenous and oral alfentanil as a noninvasive probe for hepatic and first-pass CYP3A activity

2004 Clinical Pharmacology & Therapeutics
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Role of CYP3A in the metabolism, disposition and clinical effects of methadone in humans

2003 Clinical Pharmacology & Therapeutics
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Citations (1)