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Brian Sherer
Brian Sherer
Merck Serono
Biochemistry
Chemistry
Bruton's tyrosine kinase
Covalent bond
Tyrosine kinase
6
Papers
79
Citations
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Synthesis and SAR development of quinoline analogs as novel P2X7 receptor antagonists
2019
Bioorganic & Medicinal Chemistry Letters
Yufang Xiao
Srinivasa Karra
Andreas Goutopoulos
Noune Tahmassian Morse
Susan Zhang
Mohanraj Dhanabal
Hui Tian
Jeyaprakashnarayanan Seenisamy
Jayashankaran Jayadevan
Richard D. Caldwell
Justin Potnick
Matthew Bleich
Eugene Chekler
Brian Sherer
Venkataraman Sriraman
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Citations (5)
Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors
2018
Bioorganic & Medicinal Chemistry Letters
Hui Qiu
Lesley Liu-Bujalski
Richard D. Caldwell
Ariele Viacava Follis
Anna S. Gardberg
Andreas Goutopoulos
Roland Grenningloh
Jared Head
Theresa L Johnson
Christopher Charles Victor Jones
Reinaldo Jones
Igor Mochalkin
Federica Morandi
Constantin Neagu
Justin Potnick
Brian Sherer
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Citations (5)
Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk
2018
Bioorganic & Medicinal Chemistry Letters
Richard D. Caldwell
Lesley Liu-Bujalski
Hui Qiu
Igor Mochalkin
Reinaldo Jones
Constantin Neagu
Andreas Goutopoulos
Roland Grenningloh
Theresa L Johnson
Brian Sherer
Anna S. Gardberg
Ariele Viacava Follis
Federica Morandi
Jared Head
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Citations (9)
Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit.
2018
Bioorganic & Medicinal Chemistry Letters
Hui Qiu
Lesley Liu-Bujalski
Richard D. Caldwell
Ariele Viacava Follis
Anna S. Gardberg
Andreas Goutopoulos
Roland Grenningloh
Jared Head
Theresa L Johnson
Reinaldo Jones
Igor Mochalkin
Federica Morandi
Constantin Neagu
Brian Sherer
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Citations (13)
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