author-photo

W. Rycroft

Merck & Co.

22

Papers

1441

Citations

Citation Trend

Filter By

Papers (17) Sort By

Journal Conference Others

N-Heteroaryl-2-phenyl-3-(benzyloxy)piperidines: A Novel Class of Potent Orally Active Human NK1 Antagonists.

2010 ChemInform
Show All
- Source
- Cite
- Save
Citations (0)
Novel lactam NK1 antagonists with anti-emetic activity

2006 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (1)
An Inverse Agonist Selective for 5 Subunit-Containing GABAA Receptors Enhances Cognition

2006
Show All
- Source
- Cite
- Save
Citations (0)
An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

2005 Journal of Pharmacology and Experimental Therapeutics
Show All
- Source
- Cite
- Save
Citations (216)
4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II

2002 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (25)
2-Aryl indole NK1 receptor antagonists: optimisation of the 2-Aryl ring and the indole nitrogen substituent

2001 Bioorganic & Medicinal Chemistry Letters
Show All
- Source
- Cite
- Save
Citations (43)
The novel NK1 receptor antagonist MK-0869 (L-754,030) and its water soluble phosphoryl prodrug, L-758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets

2000 Neuropharmacology
Show All
- Source
- Cite
- Save
Citations (131)
Structural Optimization Affording 2-(R)-(1-(R)-3,5-Bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a Potent, Orally Active, Long-Acting Morpholine Acetal Human NK-1 Receptor Antagonist

1998 Journal of Medicinal Chemistry
Show All
- Source
- Cite
- Save
Citations (173)
Prediction of the anti-emetic activity of NK-1 receptor antagonists in ferrets by their ability to inhibit GR73632-induced foot tapping in gerbils

1997
Show All
- Source
- Cite
- Save
Citations (0)
Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets

1996 Neuropharmacology
Show All
- Source
- Cite
- Save
Citations (200)