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Mercedes Villarroya

Autonomous University of Madrid

79

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3036

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Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia

2017 European Journal of Medicinal Chemistry
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New Melatonin–N,N-Dibenzyl(N-methyl)amine Hybrids: Potent Neurogenic Agents with Antioxidant, Cholinergic, and Neuroprotective Properties as Innovative Drugs for Alzheimer’s Disease

2014 Journal of Medicinal Chemistry
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Dibenzo[1,4,5]thiadiazepine: A hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases

2014 European Journal of Medicinal Chemistry
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ITH12410/SC058: A New Neuroprotective Compound with Potential in the Treatment of Alzheimer's Disease

2014 ACS Chemical Neuroscience
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Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents

2013 MedChemComm
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Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

2013 Neuropharmacology
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Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry.

2012 ACS Chemical Neuroscience
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Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles.

2011 Bioorganic & Medicinal Chemistry
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Synthesis and pharmacological assessment of diversely substituted pyrazolo(3,4-b)quinoline, and benzo(b)pyrazolo(4,3-g)(1,8)naphthyridine derivatives

2011 European Journal of Medicinal Chemistry
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N-Acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s disease

2011 European Journal of Medicinal Chemistry
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