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Douglas S Compton

Schering-Plough

20

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Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats

2003 British Journal of Pharmacology
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Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

2001 British Journal of Pharmacology
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The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys

2001 European Journal of Pharmacology
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Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Inhibits the Development of Atherosclerosis in ApoE Knockout Mice

2001 Arteriosclerosis, Thrombosis, and Vascular Biology
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The cholesterol absorption inhibitor ezetimibe inhibits the development of atherosclerosis in apo E knockout (−/−) mice fed low fat and western diets

2000 Atherosclerosis
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The potent cholesterol absorption inhibitor, ezetimibe, is glucuronidated in the intestine, localizes to the intestine, and circulates enterohepatically

2000 Atherosclerosis
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The novel cholesterol absorption inhibitor, ezetimibe, selectively inhibits the intestinal absorption of free cholesterol in the presence and absence of exocrine pancreatic function

2000 Atherosclerosis
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Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663.

2000 British Journal of Pharmacology
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Rapid normalization of pre-established hypercholesterolemia in rhesus monkeys by the potent cholesterol absorption inhibitor ezetimibe (SCH58235)

2000 Atherosclerosis
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In Vivo Metabolism-Based Discovery of a Potent Cholesterol Absorption Inhibitor, SCH58235, in the Rat and Rhesus Monkey through the Identification of the Active Metabolites of SCH48461

1997 Journal of Pharmacology and Experimental Therapeutics
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