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Larry H. Matherly

Wayne State University

223

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Folate transporter dynamics and therapy with classic and tumor-targeted antifolates.

2021 Scientific Reports
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EPV002/#308 Metabolomic adaptations associated with chemoresistance in ovarian cancer cell lines

2021
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Lipid metabolism reprogramming in renal cell carcinoma.

2021 Cancer and Metastasis Reviews
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A Novel Isoflavone, ME-344, Enhances Venetoclax Antileukemic Activity Against AML Via Suppression of Oxidative Phosphorylation and Purine Biosynthesis

2021 Blood
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Therapeutic Targeting of Mitochondrial One-Carbon Metabolism in Cancer.

2020 Molecular Cancer Therapeutics
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RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.

2020 International Journal of Molecular Sciences
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Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds.

2020 British Journal of Cancer
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Design, synthesis and biological evaluation of novel pyrrolo[2,3-d]pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors over the reduced folate carrier

2020 Bioorganic & Medicinal Chemistry
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Portfolio Review in Graduate Admissions: Outcomes of a Pilot Program.

2019
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Abstract 4794: Targeting mitochondrial and cytosolic one carbon metabolism of pancreatic adenocarcinoma via the proton-coupled folate transporter with novel 5-substituted pyrrolo[3,2-d]pyrimidine analogs

2019 Cancer Research
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