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    Characterisation of the initial period of protein adsorption by dynamic surface tension measurements using different drop techniques
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    Keywords:
    Globular protein
    Protein Adsorption
    Denaturation (fissile materials)
    ABSTRACT Mechanisms involved in the formation of three‐dimensional networks of globular proteins are discussed in general terms. Denaturation and aggregation of soy proteins under various conditions were studied. Differential scanning calorimetry was used in the denaturation, and turbidity measurements in the aggregation studies. Conditions favoring denaturation, such as high and low pH, had the opposite effect on aggregation. Salt was found to have a special effect on the behavior of soy proteins, suppressing aggregation as well as denaturation, probably due to its stabilizing influence on the quaternary structure. Viscometric studies of the progel state of soy protein gels showed that the onset of the progel is closely related to the denaturation process. Some commercial isolates were found to be completely denatured. Despite forming firm gels after cooling, they did not appear to have a progel state.
    Denaturation (fissile materials)
    Globular protein
    Turbidity
    Globular protein
    Cooperativity
    Denaturation (fissile materials)
    Molten globule
    It is shown that microwave irradiation can affect the kinetics of the folding process of some globular proteins, especially beta-lactoglobulin. At low temperature the folding from the cold denatured phase of the protein is enhanced, while at a higher temperature the denaturation of the protein from its folded state is enhanced. In the latter case, a negative temperature gradient is needed for the denaturation process, suggesting that the effects of the microwaves are nonthermal. This supports the notion that coherent topological excitations can exist in proteins. The application of microwaves hold promises for a wide range of biotechnological applications, such as protein synthesis, protein aggregation, etc., and may have implications for biological systems as well.
    Globular protein
    Denaturation (fissile materials)
    Folding (DSP implementation)
    Citations (182)
    Abstract GuHCl denaturation profiles of 17 proteins were studied by the spectroscopic and chromatographic methods described in the preceding report. The profiles are broadly classified into three types according to their multiphasic characteristics. It seems likely that more complex processes than those previously accepted take place in the denaturational conformation change of proteins.
    Denaturation (fissile materials)
    Globular protein
    Citations (39)